It depends on what you mean.

The standard markers retain their output (paper space) size relative to the scale of the model (they are bigger at 1/8" than 1/4" scale).

If you are looking for markers that stay the same size relative to the model (regardless of scale) you do this by changing the scale of the drawing on the layout (though this is a bad habit to get into).

If you want markers that repsond to the scale by changing size, content, etc in a non-linear fashion these would have to be custom coded.